Russian opposition figure Alexei Navalny is unconscious in hospital suffering from suspected poisoning, his spokeswoman has said.
The anti-corruption campaigner fell ill during a flight and the plane made an emergency landing in Omsk, Kira Yarmysh said, adding that they suspected something had been mixed into his tea.
The hospital said Mr Navalny was in a stable but serious condition.
Mr Navalny, 44, is a staunch critic of President Vladimir Putin.
In June he described a vote on constitutional reforms as a "coup" and a "violation of the constitution". The reforms allow Mr Putin to serve another two terms in office.
What has the spokeswoman said?
Kira Yarmysh, the press secretary for the Anti-Corruption Foundation, which Mr Navalny founded in 2011, tweeted: "This morning Navalny was returning to Moscow from Tomsk.
"During the flight, he felt ill. The plane made an urgent landing in Omsk. Alexei has toxic poisoning. Right now we are going to hospital."
She added: "We suspect that Alexei was poisoned by something mixed into [his] tea. It was the only thing he drank since morning.
"Doctors are saying that the toxic agent absorbed faster through the hot liquid. Right now Alexei is unconscious."
Ms Yarmysh later tweeted that Mr Navalny was on a ventilator and in a coma.
She said doctors were initially ready to share any information but were now saying the toxicology tests were delayed and were "clearly playing for time, and not saying what they know".
The hospital was now full of police officers, she said.
What are the other reports from the scene?
The Tass news agency quoted one source at the Omsk Emergency Hospital as saying: "Alexei Anatolyevich Navalny, born in 1976. Poisoning intensive care."
However, the deputy head physician of the hospital later told media that it was not certain Mr Navalny had been poisoned, although "natural poisoning" was one of the diagnoses being considered.
Anatoly Kalinichenko said Mr Navalny was in a stable and serious condition, but did not comment on the threat to his life.
Video footage on social media shows Mr Navalny being taken on a stretcher to an ambulance on the airport runway.
Other disturbing video appears to show a stricken Mr Navalny in pain on the flight.
Passenger Pavel Lebedev said: "At the start of the flight he went to the toilet and didn't come back. He started feeling really sick. They struggled to bring him round and he was screaming in pain."
Another photograph on social media purports to show Mr Navalny drinking from a cup at a Tomsk airport cafe.
The Interfax agency said the cafe owners were checking CCTV to see if it could provide any evidence.
Who is Alexei Navalny?
He made a name for himself by exposing official corruption, labelling Mr Putin's United Russia as "the party of crooks and thieves", and has served several jail terms.
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In 2011 he was arrested and imprisoned for 15 days following protests over vote-rigging by Mr Putin's United Russia party in parliamentary elections.
Mr Navalny was briefly jailed in July 2013 on embezzlement charges but denounced the sentence as political.
He attempted to stand in the 2018 presidential race but was barred because of previous fraud convictions in a case he again said was politically motivated.
Mr Navalny was also given a 30-day jail term in July 2019 after calling for unauthorised protests.
He was taken ill during that jail sentence. Doctors diagnosed him with "contact dermatitis" but he said he had never had any acute allergic reactions and his own doctor suggested he might have been exposed to "some toxic agent". Mr Navalny also said he thought he may have been poisoned.
Mr Navalny also suffered a serious chemical burn to his right eye in 2017 after he was assaulted with antiseptic dye.
Last year his Anti-Corruption Foundation was officially declared a "foreign agent", enabling the authorities to subject it to more checks.
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